First off let me address this from the very start, House Dust Mites are not a pest control issue. We deal with them in connection with Bed Bugs from time to time and really only as a matter of mattress or box spring encasements. I wanted to address this bug in that manner, encasements are the way to go with this bug.
Our homes are their homes, they love human and pet dander or skin flakes. This debris will fall everywhere, carpets, bedding, furniture and furniture. This dust or debris will become airborne and vacuuming is essential in keeping things in check. Along with cockroach skins and dust mites excrement may cause asthma or breathing issues.
A gram of dust vacuumed from carpeting may contain 100-400 and 1 gram of dust vacuumed from furniture may contain 3500 mites.
Encasements are a great way to protect your mattress or box spring investment and keep the dust mites out. Control is possible but it is a ongoing management concern.